Results ofin vivoandin vitrostudies for assessing prenatal toxicity

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Results of in vivo and in vitro studies for assessing prenatal toxicity

Examples of a combined approach using in vivo as well as in vitro methods for the assessment of prenatal toxicity are presented. The topics discussed include the analysis of the possible embryotoxic potential of valproic acid (VPA), female sex hormones, bis(tri-n-butyltin) oxide (TBTO), and acyclovir and the problem of supplementing in vitro systems with drug-metabolizing activity.

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 1986

ISSN: 0091-6765,1552-9924

DOI: 10.1289/ehp.867089